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TerSera NurseSupport Doctor Discussion Guide

How to get started with XERMELO

In a clinical trial, many patients saw significant improvement at 12 weeks

Some patients may start to see results within three weeks

In the 12-week study, patients reported improvement in their diarrhea symptoms, primarily a reduction in bowel movement (BM) frequency. However, you could see results as early as three weeks. Learn more about the 12-week study.

Continue taking XERMELO as advised by your doctor, even if symptoms improve

It’s important to continue taking XERMELO three times a day, every day.

Take XERMELO three times a day, every day, with food

You need to take XERMELO 3 times a day, every day, with a meal or snack. That’s because food increases your body’s ability to absorb XERMELO.

3X DAILY with fork and knife criss-crossed 3X DAILY with fork and knife criss-crossed
Icon of person from neck down holding painful stomach

Symptoms may return if you miss a dose of XERMELO.

Easy and convenient packaging — first dose and every dose

When it comes to managing your carcinoid syndrome diarrhea (CSD), XERMELO helps make it easy to remember and track every dose. XERMELO comes in a monthly pack with 4 convenient blister packs (one per week).

Tips for taking XERMELO

  • Carry it with you while you’re on the go
  • Set reminders on your phone, or sign up with a Clinical Nurse Educator to receive reminder text messages
  • Write down reminders in a journal or planner
Actor portrayals of female patient in green shirt talking to female doctor, pointing to Doctor Discussion Guide Actor portrayals of female patient in green shirt talking to female doctor, pointing to Doctor Discussion Guide Actor portrayals.

How to talk to your doctor about XERMELO

Complete a few questions and download your answers to create a helpful discussion guide for your next appointment.

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How to get XERMELO

TerSera SupportSource has many resources to help

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Co-pay support

You could pay as little as $0 co-pay* if you have commercial insurance

See if you’re eligible

Starting on XERMELO?

TerSera NurseSupport is here to help with every step

Contact a nurse

* For eligible commercially insured patients, the co‑pay card is subject to an annual limit. You are not eligible if prescriptions are paid for by any state or other federally funded programs, including, but not limited to, Medicare or Medicaid, Medigap, VA or DOD or TriCare, or where prohibited by law.

Important Safety Information

  • Do not take XERMELO if you have a history of hypersensitivity to telotristat or any of the ingredients in XERMELO.
  • XERMELO may cause constipation which can be serious. You should stop taking XERMELO if severe constipation or severe, persistent, or worsening abdominal pain develops. Talk to your doctor if you have these symptoms.
  • Do not take XERMELO if you have a history of hypersensitivity to telotristat or any of the ingredients in XERMELO.
  • XERMELO may cause constipation which can be serious. You should stop taking XERMELO if severe constipation or severe, persistent, or worsening abdominal pain develops. Talk to your doctor if you have these symptoms.
  • The most common side effects of XERMELO include nausea, headache, increase in liver enzymes, depression, flatulence, decreased appetite, swelling of your hands and feet, fever, abdominal pain, and constipation.
  • Talk to your doctor about all medications you are taking as some may interact with XERMELO.
  • XERMELO is not recommended if you have moderate or severe liver impairment.

Indication

XERMELO is a prescription pill, used along with somatostatin analog (SSA) therapy, for carcinoid syndrome diarrhea in adults who are not adequately controlled by SSA therapy.

You are encouraged to report negative side effects of prescription drugs to the FDA. To report suspected adverse reactions, contact the FDA at 1‑800‑FDA‑1088 or www.FDA.gov/medwatch. You may also contact TerSera Therapeutics at 1‑844‑334‑4035 or medicalinformation@tersera.com.

Please see Full Prescribing Information.

 

Important Safety Information

  • Do not take XERMELO if you have a history of hypersensitivity to telotristat or any of the ingredients in XERMELO.
  • XERMELO may cause constipation which can be serious. You should stop taking XERMELO if severe constipation or severe, persistent, or worsening abdominal pain develops. Talk to your doctor if you have these symptoms.
  • Do not take XERMELO if you have a history of hypersensitivity to telotristat or any of the ingredients in XERMELO.
  • XERMELO may cause constipation which can be serious. You should stop taking XERMELO if severe constipation or severe, persistent, or worsening abdominal pain develops. Talk to your doctor if you have these symptoms.
  • The most common side effects of XERMELO include nausea, headache, increase in liver enzymes, depression, flatulence, decreased appetite, swelling of your hands and feet, fever, abdominal pain, and constipation.
  • Talk to your doctor about all medications you are taking as some may interact with XERMELO.
  • XERMELO is not recommended if you have moderate or severe liver impairment.

Indication

XERMELO is a prescription pill, used along with somatostatin analog (SSA) therapy, for carcinoid syndrome diarrhea in adults who are not adequately controlled by SSA therapy.

You are encouraged to report negative side effects of prescription drugs to the FDA. To report suspected adverse reactions, contact the FDA at 1-800-FDA-1088 or www.FDA.gov/medwatch. You may also contact TerSera Therapeutics at 1-844-334-4035 or medicalinformation@tersera.com.

Please see Full Prescribing Information.

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